Condition

Depression

Depression is a common mental health condition that causes persistent feelings of sadness, loss of interest, and other symptoms. It's a treatable medical condition that affects how you think, feel, and function.

Eir.Space Medical AI
Reviewed by Medical AI
Last reviewed: January 20, 2025
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Overview#

Depression, also known as major depressive disorder, is a common and serious medical condition that negatively affects how you feel, think, and act. It causes feelings of sadness and/or a loss of interest in activities you once enjoyed. Depression can lead to a variety of emotional and physical problems and can decrease your ability to function at work and at home.

Depression is not a sign of weakness or a character flaw. It's a real medical condition with biological, psychological, and social causes. The good news is that depression is highly treatable, and most people who receive treatment experience significant improvement.

Symptoms#

Depression symptoms can vary from mild to severe and may include:

  • Persistent sad, anxious, or "empty" mood
  • Loss of interest or pleasure in activities once enjoyed
  • Feelings of hopelessness or pessimism
  • Irritability
  • Feelings of guilt, worthlessness, or helplessness
  • Decreased energy or fatigue
  • Difficulty concentrating, remembering, or making decisions
  • Sleep disturbances (insomnia or sleeping too much)
  • Appetite or weight changes
  • Thoughts of death or suicide, or suicide attempts
  • Aches or pains, headaches, or digestive problems without a clear physical cause

Symptoms must last at least two weeks and represent a change in your previous level of functioning for a diagnosis of depression.

When to Seek Immediate Care#

Seek emergency help immediately if:

  • You have thoughts of harming yourself or others
  • You're experiencing severe depression symptoms
  • You're unable to care for yourself or others
  • You're having thoughts of suicide

Crisis Resources:

  • Call 112 (Sweden) or your local emergency number
  • National Suicide Prevention Lifeline: Available 24/7
  • Contact a mental health professional immediately

Self-care & Home Management#

While professional treatment is important, self-care strategies can help manage symptoms:

  1. Stay Connected:

    • Maintain relationships with family and friends
    • Join support groups
    • Avoid isolation
  2. Physical Activity:

    • Regular exercise can help improve mood
    • Even light activity like walking can help
    • Aim for 30 minutes most days
  3. Sleep Hygiene:

    • Maintain a regular sleep schedule
    • Create a relaxing bedtime routine
    • Avoid screens before bed
  4. Healthy Eating:

    • Eat regular, balanced meals
    • Limit alcohol and caffeine
    • Stay hydrated
  5. Stress Management:

    • Practice relaxation techniques (meditation, deep breathing)
    • Set realistic goals
    • Break large tasks into smaller ones
  6. Avoid Alcohol and Drugs:

    • These can worsen depression
    • Can interfere with medications

When to Seek Care#

Contact Healthcare Provider#

  • Symptoms lasting more than two weeks
  • Symptoms interfering with daily life
  • Thoughts of self-harm or suicide
  • Difficulty functioning at work or home
  • Physical symptoms without clear cause
  • Need for medication or therapy adjustment

Self-care is Appropriate#

  • Mild symptoms that don't interfere with daily life
  • Following treatment plan as prescribed
  • Symptoms improving with current treatment

Tests & Diagnostics#

Diagnosing depression involves:

  1. Clinical Assessment:

    • Discussion of symptoms, thoughts, feelings, and behavior patterns
    • Medical history review
    • Family history of mental health conditions
  2. Physical Examination:

    • Rule out physical causes of symptoms
    • Check for underlying medical conditions
  3. Laboratory Tests:

    • Blood tests to rule out thyroid problems, vitamin deficiencies
    • May check for other medical conditions
  4. Psychological Evaluation:

    • Questionnaires or screening tools
    • Assessment of mental status

There's no single test for depression. Diagnosis is based on symptoms, medical history, and clinical evaluation.

Treatment#

Depression is highly treatable. Treatment options include:

  1. Psychotherapy (Talk Therapy):

    • Cognitive Behavioral Therapy (CBT)
    • Interpersonal Therapy (IPT)
    • Problem-solving therapy
    • Can be individual, group, or family therapy
  2. Medications:

    • Antidepressants (SSRIs, SNRIs, others)
    • May take 4-8 weeks to see full effect
    • Often combined with therapy
  3. Lifestyle Changes:

    • Regular exercise
    • Healthy diet
    • Adequate sleep
    • Stress reduction
  4. Other Treatments (for severe cases):

    • Electroconvulsive therapy (ECT)
    • Transcranial magnetic stimulation (TMS)
    • Light therapy (for seasonal depression)

Treatment is often most effective when combining medication and therapy. Finding the right treatment may take time and patience.

Prevention#

While depression can't always be prevented, you can reduce your risk:

  • Manage Stress: Learn healthy coping strategies
  • Stay Connected: Maintain strong social connections
  • Get Treatment Early: Don't wait for symptoms to worsen
  • Take Care of Physical Health: Exercise, sleep, nutrition
  • Avoid Alcohol and Drugs: These can trigger or worsen depression
  • Know Your Risk Factors: Family history, life changes, medical conditions

What Happens in the Body#

Depression involves changes in brain chemistry and function:

  • Neurotransmitter Imbalance: Changes in serotonin, norepinephrine, dopamine
  • Brain Structure: Some areas may be smaller or less active
  • Hormonal Changes: Stress hormones, thyroid hormones
  • Inflammation: Some research suggests inflammation may play a role

These biological changes interact with psychological and social factors to cause depression symptoms.

Life-stage Considerations#

Children and Adolescents#

  • May show different symptoms (irritability, behavior problems)
  • School performance may decline
  • May have physical complaints
  • Requires specialized pediatric mental health care

Older Adults#

  • May be mistaken for normal aging
  • Often underdiagnosed and undertreated
  • May have different symptoms (memory problems, physical complaints)
  • Can be triggered by medical conditions or medications

Pregnancy and Postpartum#

  • Hormonal changes can trigger depression
  • Postpartum depression is common and treatable
  • Important to seek help for both mother and baby's wellbeing

FAQ#

Is depression the same as sadness?#

No. While sadness is a normal emotion, depression is a medical condition that persists and interferes with daily life. Depression involves multiple symptoms and lasts for weeks or months.

Can depression go away on its own?#

Sometimes mild depression may improve, but moderate to severe depression usually requires treatment. Without treatment, depression can worsen and last for months or years.

Do antidepressants change your personality?#

No. Antidepressants help restore normal brain function and reduce symptoms. They don't change who you are as a person.

How long does treatment take?#

Most people see improvement within 4-8 weeks of starting treatment. Full recovery may take several months. Some people may need long-term treatment.

Can you prevent depression?#

While you can't always prevent depression, maintaining good mental health habits, managing stress, staying connected, and seeking help early can reduce your risk.

Understand Your Own Health Records

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